NOS knockouts and neuroprotection
Article Abstract:
Different isoforms of nitric oxide synthase may be involved in the development of neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease. Nitric oxide is a free radical and can produce oxidative damage in the brain.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
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Heme moves to center stage in cerebral malaria
Article Abstract:
A new therapeutic approach to treat cerebral malaria suggests that the enzyme heme oxygenase-1 (OH-1) or its product carbon monoxide could decrease free heme level that induce inflammation and permeabilization of the blood brain barrier, leading to death.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
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