Drug therapy: the diagnosis and management of insomnia
Article Abstract:
Insomnia, the inability to sleep, is a common sleep disorder, which may result from several causes and vary extensively in duration and severity. The events in one's life, medications, psychological and medical factors may cause insomnia and should be assessed upon diagnosis. People who usually sleep well but experience stress, environmental change, jet lag or drug side effects may have transient, short-term insomnia, whereas chronic insomnia tends to result from a medical or psychological problems. Treatment should be directed at the underlying causes, and may involve withdrawal of substances causing side effects, management of stress, counseling, and various psychotherapeutic techniques. Sleeping pills may be used for transient, short-term insomnia, but are not recommended for long-term treatment. Benzodiazepines are the drugs of choice for insomnia, and consist of various long- and short-acting forms. Long-acting drugs such as flurazepam produce sedative hangover effects the next day, whereas short-acting agents such as triazolam may worsen the insomnia and cause a form of amnesia. Because side effects are related to dose, the dose should be kept low. When prescribing hypnotics, a physician should take into consideration the patient's age and lifestyle and duration of treatment, and avoid large or renewable prescriptions. Depressed or suicidal patients, alcohol or substance abusers, the elderly and mentally impaired, patients with sleep-related breathing disorders and incurable insomnia, and pregnant women require special attention. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1990
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Chronic Insomnia
Article Abstract:
A preliminary report of a June 2005 conference on insomnia reveals that both cognitive behavioral therapy and benzodiazepine-receptor agonists are effective in treating insomnia, though the long-term effectiveness of the agonists requires further study. Cognitive behavioral therapy should not be combined with the use of hypnotic agents as such an approach reduces the long-term benefit of cognitive behavioral therapy.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
User Contributions:
Comment about this article or add new information about this topic: