Effect of Statins on Risk of Coronary Disease: A Meta-analysis of Randomized Controlled Trials
Article Abstract:
Statin drugs appear to have decreased the risk of heart attack and also mortality rates in people with high cholesterol levels. Statins are drugs that lower blood cholesterol and include lovastatin, pravastatin and simvastatin. Researches used meta-analysis to evalute five clinical trials of statin drugs covering 30,817 patients. The drugs lowered cholesterol 20%, LDL-cholesterol 28%, and triglycerides 13%. They reduced the risk of heart attack about 31% and mortality rates about 21%. These reductions were seen in women as well as men.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
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Antibiotic therapy for coronary artery disease: can a WIZARD change it all?
Article Abstract:
More research is needed to determine whether antibiotics can lower the risk of premature death in people who have coronary artery disease. Laboratory research and animal studies have shown that a bacteria called Chlamydia pneumoniae may be involved in coronary artery disease. However, antibiotic therapy has not always reduced the death rate from coronary artery disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
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Effects of antibiotic therapy on outcomes of patients with coronary artery disease: A meta-analysis of randomized controlled trials
Article Abstract:
A study to conduct a meta-analysis of clinical trials of antichlamydial antibiotic therapy in patients with coronary artery disease is presented. The outcome suggests that evidence available to date does not demonstrate an overall benefit of antibiotic therapy in reducing mortality or cardiovascular events in patients with coronary artery disease.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
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