Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome

Article Abstract:

A protective form of mechanical ventilation appears to lead to better outcomes than traditional ventilation in patients with acute respiratory distress syndrome. Animal studies have shown that traditional ventilation can damage the lungs. Researchers compared traditional ventilation with a protective-ventilation strategy in 53 patients with acute respiratory distress syndrome. Survival rates at 28 days were much higher in the group receiving protective ventilation and they were more likely to be weaned from the ventilator. However, survival rates at hospital discharge were not significantly different.

Patient outcomes, Mortality

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Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome

Article Abstract:

The administration of perflubron during artificial ventilation may be effective in the treatment of premature infants with respiratory distress syndrome. Perflubron is liquid perfluorocarbon that is chemically inert and can carry oxygen and carbon dioxide. It was given to 10 premature infants in severe respiratory distress in combination with artificial ventilation. It improved the function of their lungs and increased their blood levels of oxygen. Seven infants were eventually weaned off the ventilator and at the age of 4 months, six had developed normally with no sign of cerebral palsy.

Health aspects, Infants (Premature), Premature infants, Perfluorocarbons

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Culmination of an era in research on the acute respiratory distress syndrome

Article Abstract:

Doctors who treat patients with acute respiratory distress syndrome (ARDS) should decrease the amount of air delivered by the ventilator. ARDS is caused by a buildup of fluid in the lungs because they have been damaged. Many patients will die unless they are placed on a ventilator, which provides oxygen while the lungs heal. Traditionally, the ventilator is set to provide slightly more air to the lungs than normal to make sure the patient receives enough oxygen. But this can damage the lungs. A study published in 2000 showed that reducing the amount of air can lower mortality rates.

Editorial

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