Effect of antihypertensive therapy on the kidney in patients with diabetes: a meta-regression analysis

Article Abstract:

Angiotensin-converting enzyme (ACE) inhibitors may reduce the risk of kidney failure in patients suffering from diabetes. ACE inhibitors are a group of drugs used to treat hypertension. A survey of the medical literature found that treatment with ACE inhibitors reduces the level of protein in the urine of diabetes patients. This reduction occurred regardless of the effect of the ACE inhibitor on blood pressure, the type of diabetes or the stage of kidney disease. Treatment with ACE inhibitors also preserved normal kidney function regardless of their effect on blood pressure. Other antihypertensive drugs reduced the levels of protein in the urine in diabetes patients, but this change was dependent on reductions in blood pressure. Other antihypertensive drugs also impaired kidney function. Hypertension is a condition that can lead to the development of kidney failure in diabetes patients suffering from kidney disease.

Hypertension, Physiological aspects, Drug therapy, ACE inhibitors, Angiotensin converting enzyme inhibitors, Kidneys, Kidney

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The kidney in cardiovascular disease

Article Abstract:

Kidney disease can increase a person's risk of heart disease. This could be the result of an underlying vascular disease that affects both kidneys and heart. Or the kidney disease may cause metabolic abnormalities that can adversely affect the heart.

Editorial

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Trial of a drug to decrease the risk for heart disease in patients with mild kidney failure

Article Abstract:

Mild kidney disease can increase a person's risk of heart disease, according to a study of 9,297 patients. The study also showed that the ACE inhibitor ramipril can reduce this risk.

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