Effect of systemic glucocorticoids on exacerbations of chronic obstructive pulmonary disease
Article Abstract:
Corticosteroids appear to have a moderate benefit when used to treat exacerbations of chronic obstruction pulmonary disease (COPD) but the effect does not last long. Researchers randomly assigned 271 hospital patients with COPD exacerbations to receive placebo, two weeks of intravenous and oral methylprednisolone, or eight weeks of intravenous and oral methylprednisolone. Those who received methylprednisolone had shorter hospital stays and better lung function. However, six months later there was no difference in lung function among all three groups. Those who received methylprednisolone were more likely to develop elevated blood sugar levels.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
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Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease
Article Abstract:
Doctors should consider giving corticosteroid drugs for 10 days to all patients hospitalized with an acute exacerbation of chronic obstructive pulmonary disease (COPD), according to a study published in 2003. An acute exacerbation of any disease means the symptoms become worse than normal in a short period of time. Corticosteroid drugs have serious side effects and probably should not be taken for long periods of time.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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The diagnosis and treatment of cough
Article Abstract:
Colds, hay-fever, sinusitis, chronic obstructive lung disease, and whooping cough are the most common causes of cough. A persistent cough is commonly caused by asthma, post-nasal drip syndrome and gastroesophageal reflux. The diagnosis and management of cough is reviewed.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
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