Effect of vitamin E and beta carotene on the incidence of angina pectoris: a randomized, double-blind, controlled trial

Article Abstract:

Vitamin E supplementation may slightly decrease the incidence of chest pain known as angina pectoris, however beta carotene supplementation may slightly increase the incidence of angina pectoris. Research suggests that vitamin E and beta carotene may prevent the hardening of arteries which can cause chest pain and coronary artery disease. Of 22,269 male smokers with no history of chest pain or heart attack, 5,570 took a daily supplement of vitamin E, 5,602 took a daily supplement of beta carotene, 5,548 took both supplements, and 5,549 took a placebo. During a median follow-up of 4.7 years, 1,983 new cases of angina pectoris developed. Compared to the incidence of angina in the placebo group, the incidence was 3% lower in the vitamin E group, 13% higher in the beta carotene group, and 4% lower in the vitamin E plus beta carotene group.

Vitamin E, Beta carotene, Angina pectoris

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Insulin, glucose, insulin resistance, and pancreatic cancer in male smokers

Article Abstract:

An investigation on whether prediagnostic fasting glucose and insulin concentrations and insulin resistance are associated with subsequent incidence of exocrine pancreatic cancer in a cohort of male smokers is presented. Results support the hypothesis that exposure to higher insulin concentrations and insulin resistance predicts the risk of exocrine pancreatic cancer.

Diagnosis, Risk factors, Medical examination, Smokers, Pancreatic cancer, Insulin resistance

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Cause-specific excess deaths associated with underweight, overweight, and obesity

Article Abstract:

The estimates from cause-specific excess deaths associated with underweight body mass index (BMI) were found to vary considerably by cause of death.

Mortality, Obesity, Body mass index, Clinical report

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