Effects of maternal ingestion of low-dose aspirin on the fetal cardiovascular system

Article Abstract:

The cardiovascular system of a developing fetus may not be affected by daily maternal ingestion of a low dose of aspirin. Low-dose aspirin may reduce the risk of preeclampsia or fetal growth retardation in pregnant women with lupus anticoagulant or anticardiolipin antibodies. A study compared 15 fetuses whose mothers ingested 87 milligrams of aspirin per day to 26 fetuses whose mothers did not use aspirin. Ultrasonography and range-gated, pulsed Doppler echocardiography were used to examine the central and regional blood circulation of the developing fetuses every four weeks starting as early as the 12th week of pregnancy. No difference in central or regional blood circulation was found between the two groups. Preeclampsia is a condition that occurs in late pregnancy that can lead to the development of convulsions or coma.

Fetus, Pregnant women, Drug use, Aspirin

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M-mode echocardiographic evaluation of fetal and infant hearts: longitudinal follow-up study from intrauterine life to year one

Article Abstract:

It appears that the human heart adapts to the transition to life outside the womb and during the first year of life by increasing the size of the ventricles. Researchers used echocardiography to periodically assess heart anatomy and function in 52 normal fetuses beginning as early as 16 weeks gestation and ending at 12 months old. Heart rate decreased during pregnancy and after birth without a change in ventricular ejection fraction and without a change in contractility. This suggests that the ventricles adapt by increasing in size.

Analysis, Usage, Adaptation (Biology), Evolutionary adaptation, Echocardiography, Fetal heart

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The preterm prediction study: maternal stress is associated with spontaneous preterm birth at less than thirty-five weeks' gestation

Article Abstract:

Maternal stress may be a major predictor of preterm birth and low birth weight. Researchers evaluated anxiety, stress, self-esteem, mastery, and depression in 2,593 pregnant women between 25 to 29 weeks of pregnancy. Stress was independently associated with preterm birth and low birth weight. A low combined score for the other variables was not associated with preterm birth. Black women were more likely to give birth prematurely, have growth-restricted fetuses, and low birth weight infants.

Health aspects, Risk factors, Birth weight, Low, Low birth weight, Stress (Psychology), Premature birth

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