Effects of stimulus intensity and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy
Article Abstract:
Increasing the electrical dosage may improve the effectiveness of right unilateral electroconvulsive therapy. Electroconvulsive therapy is used to treat patients suffering from psychiatric disorders such as major depression. Among 96 patients suffering from depression, 23 were treated with right unilateral electroconvulsive therapy at a low dose, 23 with right unilateral electroconvulsive therapy at a high dose, 23 with bilateral electroconvulsive therapy at a low dose and 27 with bilateral electroconvulsive therapy at a high dose. Seventeen percent of the patients who received low-dose unilateral electroconvulsive therapy responded to treatment, compared with 43% of those who received high-dose unilateral therapy, 65% of those who received low-dose bilateral therapy and 63% of those who received high-dose bilateral therapy. Patients who received high-dose therapy improved faster than those who received low-dose therapy regardless of electrode placement.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1993
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Reducing suicidal ideation and depressive symptoms on depressed older primary care patients: a randomized controlled trial
Article Abstract:
Suicide rates are highest in late life and the majority of older adults who die by suicide have seen a physician in preceding months. Randomized trial known as PROSPECT (Prevention of Suicide in Primary Care Elderly: Collaborative Trial) shows that depression is the strongest risk factor for late-life suicide and for suicide's precursor, suicidal ideation.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
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Continuation Pharmacotherapy in the Prevention of Relapse Following Electroconvulsive Therapy A Randomized Controlled Trial
Article Abstract:
A combination of nortriptyline and lithium may be effective in preventing a relapse in patients with depression who have received electroconvulsive therapy (ECT). This was the conclusion of a study of 84 patients in remission after ECT. About half of all patients who receive ECT will have a relapse.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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