Evaluation of duodenogastric reflux in gallstone disease before and after simple cholecystectomy
Article Abstract:
Duodenogastric reflux (backflow of the contents of the first portion of the small intestine into the stomach) is known to occur as a complication following gastric (stomach) surgery. It has been suggested that duodenogastric reflux (DGR) may also be implicated in the development of gastric symptoms following cholecystectomy (surgical removal of the gallbladder). A study was undertaken to determine the extent of DGR in 15 patients with gallstones who underwent cholecystectomy; specimens of stomach juice were obtained before and after surgery and the bile acid content of the DGR was quantified. These results were compared with results obtained from a group of healthy control subjects. The average bile acid concentration for the control subjects was 2.25 micromoles reflux/hour, compared with 8.86 for the patient group before cholecystectomy and 24.55 for patients following surgery. No bile acid was found in either the before- or after-surgery specimens of five of the 15 surgery patients. A significant increase in bile acid was found in the remaining 10 surgical patients (67 percent). It is concluded that gallstone disease is not always associated with duodenogastric reflux; however, when it does occur, the level is higher than that of control subjects and the level increases significantly following cholecystectomy. This finding may explain some of the stomach symptoms associated with gallbladder disease, and post-cholecystectomy syndrome may be due in part to the increase in DGR. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: American Journal of Surgery
Subject: Health
ISSN: 0002-9610
Year: 1990
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Wound management update: the scientific basis of healing
Article Abstract:
Dressings that maintain tissue moisture appear to best promote the healing process and reduce the risk for infection. The unique features of each wound and patient, including the wound's location, size, and severity and the patient's immune status and clotting risk factors should help guide treatment options. A basic healing process overview and recommendations for optimal wound care is presented.
Publication Name: Physician Assistant
Subject: Health
ISSN: 8750-7544
Year: 1997
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