Endodermal sinus tumor of the ovary during pregnancy: a case report
Article Abstract:
The case history is presented of a 24-year-old pregnant woman who was diagnosed with an endodermal sinus tumor, a type of ovarian tumor usually found in children and young women. The first sign of the tumor was detected by a greatly elevated level of serum alpha-fetoprotein (AFP), a hormone associated with pregnancy. The patient underwent surgery for removal of the tumor, along with the ovary and fallopian tube on that side: lymph nodes and other tissue were also removed. The patient's levels of serum AFP were monitored throughout the remainder of the pregnancy and were noted to begin to rise again after 28 weeks' gestation. An infant was delivered by cesarean section at 33 weeks' gestation. Hyaline membrane disease (a respiratory complication) developed in the infant, but was successfully treated. The women had several tumor nodules in the pelvis and other regions. Chemotherapy (with cisplatin, etoposide, and bleomycin) was started and carried out for four 21-day cycles. Two years later, the patient was free of disease and had normal serum AFP levels. Endodermal sinus tumors should be treated both surgically and with chemotherapy, and newer chemotherapeutic protocols can result in survival rates as high as 90 percent. Combination chemotherapy using several agents, including those containing platinum, are the most effective. Information is not available regarding the effects on the fetus of this chemotherapy. Therefore, it was postponed until after delivery. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1991
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Primary hepatoid carcinoma of ovary in pregnancy
Article Abstract:
The case of a 35-year-old pregnant woman represents the first known case of hepatoid carcinoma of the ovary. Hepatoid carcinoma is a tumor similar to liver tumors that occurs in other organs. During a prenatal exam, an abdominal mass was noted. Her blood level of alpha-fetoprotein (AFP) was elevated. This can be a sign of fetal distress, but her fetus was normal. Surgery revealed a mass on her left ovary. The tumor was found to be the source of the AFP.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1998
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Acute gastric ulcer perforation in a 35 weeks' nulliparous patient with gastric banding
Article Abstract:
A case of a primiparous patient at 35 weeks' gestation with laparoscopic gastric banding, who presented to labor and delivery with protracted vomiting followed by an acute abdomen and fetal distress is discussed. An emergency surgery revealed acute gastric ulcer perforation, a complication that, although rare, should be considered.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2004
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