Erythromycin-resistant Bordetella pertussis - Yuma County, Arizona, May-October 1994
Article Abstract:
The case of a two-month-old boy with erythromycin-resistant pertussis infection illustrates that enhanced disease surveillance may characterize the spread of the drug-resistant bacterium. Pertussis or whooping cough is a respiratory disease that is caused by the Bordetella pertussis (B. pertussis) bacterium. In May, 1994, an infant in Yuma County, Arizona developed severe coughing, whooping sounds on inspiration, and vomiting. Laboratory testing confirmed B. pertussis infection and the infant was treated with oral erythromycin. His symptoms persisted, necessitating intensive care and intravenous erythromycin therapy. Susceptibility testing revealed that the B. pertussis bacterium was resistant to erythromycin. The infant was successfully treated with another antibiotic. Between late June and October 1, 1994, the Yuma County health department expanded its surveillance for pertussis. Nasopharyngeal specimens from 6 of 127 people were positive for the B. pertussis bacterium. All specimens were susceptible to erythromycin.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1995
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Four Pediatric Deaths From Community-Acquired Methicillin-Resistant Staphylococcus aureus--Minnesota and North Dakota, 1997-1999
Article Abstract:
Four cases are reported of children who died from staphylococcal infections that were resistant to methicillin. Most of these resistant strains of Staphylococcus aureus are found in hospitals and nursing homes. However, methicillin-resistant Staphylococcus aureus (MRSA) has been found in day care centers and in minority communities in other countries. These four cases occurred in Minnesota and North Dakota and three occurred in children living in rural areas. The children had none of the usual risk factors for MRSA. Doctors should treat all suspected MRSA infections with vancomycin instead of or in addition to cephalosporins.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
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Whooping Cough Caused by Bordetella pertussis and Bordetella parapertussis in an Immunized Population
Article Abstract:
Many children still develop whooping cough even though they have been vaccinated against it. Researchers tested 584 patients with symptoms of whooping cough seen at 32 health centers in Finland for the organisms that cause the disease, namely Bordetella pertussis and Bordetella parapertussis. In Finland, 98% of children receive 4 doses of pertussis vaccine. Twenty-six percent tested positive and 32% of these had B. parapertussis infection. The two organisms produced similar symptoms and B. parapertussis infection was more common in pre-school children. B. pertussis was more common in schoolchildren and adults.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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