Estrogen replacement therapy and cognitive function in older women
Article Abstract:
Estrogen replacement therapy may not preserve cognitive function in older women. Post-menopausal women are treated with estrogen to prevent heart disease. A study examined cognitive function in 800 women between 65 and 95 years old. Almost 50% of the women had received postmenopausal treatment with estrogen at some time in their life, and approximately 33% were currently receiving treatment. Cognitive function was the same in women who had received estrogen replacement therapy as in those who had not. Women treated with estrogen for long periods of time scored lower on tests assessing short-term memory. Other aspects of cognitive function were not affected by the length of treatment or the dosage of estrogen.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1993
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Hormone Replacement Therapy and Risk of Breast Cancer
Article Abstract:
Many studies of the possible link between hormone replacement therapy (HRT) and breast cancer have failed to show a consistent risk. A 1999 study showed that long-term HRT use only increased the risk of breast cancer that had a good prognosis. However, only 5% of the women in the study developed this type of breast cancer. It does not seem biologically plausible that HRT would increase the risk of one type of breast cancer but not other types. Any risk must be very small because approximately 50 years of observational data have not detected it.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
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