Ethics of phase 1 oncology studies: reexamining the arguments and data

Article Abstract:

Phase 1 studies of cancer drugs are as ethical as any other similar study. A phase 1 study of a drug is the earliest type of study and is usually done just to determine the appropriate dose. Critics say patients who participate in these studies may not benefit and must be poorly informed. However, the risks and benefits of these studies are similar to other studies and most patients understand that they may not benefit from the treatment.

Research and Development in the Physical, Engineering, and Life Sciences, Research and Testing Services, Public affairs, Cancer & Cell R&D, Ethics, Cancer research, Clinical trials, Ethical aspects, Oncology, Experimental

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Cancer researchers target angiogenesis

Article Abstract:

Researchers discussed new cancer drugs that target angiogenesis at a October, 2003 conference sponsored by the American Association for Cancer Research. Angiogenesis is the medical term for the formation of new blood vessels. Many cancer cells do this so they can grow bigger. Drugs that block this process might prevent cancer growth. More than 60 such drugs are under development in the US.

Prevention, Neovascularization

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