Overexpression of monosialoganglioside GM3 on lymphocyte plasma membrane in patients with HIV infection
Article Abstract:
HIV-infected patients appear to have an increased expression of monosialoganglioside GM3 on the surface of their T cells. Monosialoganglioside GM3 is a lipid located on the surface of blood cells. Analysis of GM3 on the T cells of 25 AIDS patients revealed that they had higher GM3 levels than 20 asymptomatic HIV-infected patients, 25 patients with other viral infections and 25 healthy volunteers. In another study, only 3 of 10 asymptomatic HIV patients developed anti-GM3 antibodies whereas all 14 patients with progressive HIV infection developed anti-GM3 antibodies.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
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Absence of edema in HIV-infected patients with end-stage renal disease
Article Abstract:
HIV-infected patients in end-stage kidney failure may not always have edema. Edema occurs when fluid accumulates in tissues. Researchers reviewed the medical records of 24 HIV-infected patients who had end-stage kidney disease. Only 11 had edema. Those with edema were less likely to have experienced diarrhea or weight loss. They were more likely to have received drug therapy for HIV. They were also more likely to have high blood pressure. However, 4 patients without edema had very low blood albumin levels.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1996
User Contributions:
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