Evidence of apoptosis in arrhythmogenic right ventricular dysplasia

Article Abstract:

Apoptosis, or cell death, may play a role in the progressive loss of heart cells in arrhythmic right ventricular dysplasia, a severe heart condition. Autopsied heart tissue of six of eight patients with arrythmic right ventricular dysplasia contained cells with DNA fragments, an indication of apoptosis. In contrast, apoptosis was absent in the right ventricles of four people who died of other causes (control group). High levels of protease CPP-32, a requirement for apoptosis, were found in the six patients positive for apoptosis. The control group and the other two heart patients had no or minimal evidence of CPP-32.

Abnormalities, Physiological aspects, Cell death, Dysplasia, Heart ventricle, Right, Right heart ventricle

---

Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy

Article Abstract:

The article discusses the significance of the endothelin B receptor in mediating the tumor endothelial barrier to T cell homing that leads to invalidation of the immunotherapy.

Science & research, Research, Endothelin, T cells, Cell adhesion, Immunotherapy

---

Similar abstracts:

• Abstracts: NICE guidance on use of topical corticosteroids in atopic eczema. Tinnitus
• Abstracts: Dofetilide in patients with congestive heart failure and left ventricular dysfunction. N-terminal pro-B-type natriuretic peptide and long-term mortality in stable coronary heart disease
• Abstracts: Brief report: the hemodynamic mechanism of pounding in the neck in atrioventricular nodal reentrant tachycardia
• Abstracts: Evaluation of a certification process for community nurses involved in sex and relationship education. Awareness of message source and its association with the impacts of sun protection campaigns in Australia
• Abstracts: Prior and current health characteristics of postmenopausal estrogen replacement therapy users compared with nonusers

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.