Experimental treatment of benign prostatic hyperplasia with transurethral balloon dilation of the prostate: preliminary study in 73 humans

Article Abstract:

Benign prostatic hyperplasia (BPH), or enlargement of the prostate, often requires surgery to treat moderate to severe symptoms. These symptoms include urinary obstructions and pain caused by the prostate exerting pressure on surrounding organs and tissues. A number of alternative treatments (to surgery) are being investigated. One of these is transurethral balloon dilation of the prostate (TUDP). It involves inserting a balloon-tipped catheter into the urethra and temporarily inflating the balloon to relieve the pressure exerted by the prostate. This study examined the effectiveness and safety of TUDP in treating 73 patients suffering from BPH. The inflation of the balloon was successful in 96 percent of the patients, and there were no complications. Seventy percent of the patients improved enough to require no further treatment; follow-up averaged 16 months. Those who failed to respond to treatment with TUDP were significantly older with greater medial lobe enlargements and greater baseline volumes of residual urine (RU). These results indicate that TUDP is a safe and effective alternative treatment for BPH. Patients exhibiting large RU volumes or greatly enlarged medial lobes are less likely to be treated successfully using this technique. Controlled clinical studies are needed to support these findings. (Consumer Summary produced by Reliance Medical Information, Inc.)

Care and treatment, Usage, Prostate diseases, Prostatic diseases, Balloon dilatation, Prostate, Prostatic hyperplasia

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Variations in acromial ossification simulating infant abuse in victims of sudden infant death syndrome

Article Abstract:

The acromial process is a structural part of the shoulder blade (scapula). Like other bony structures, it is more flexible early in life and gradually hardens (ossifies) with age. Injuries or abnormalities of the acromial process in infants are often taken to be a sign of infant abuse. In order to distinguish actual injuries related to abuse from variations in development, it is important to examine and characterize the normal variations in acromial anatomy in infants. This study examined acromial anatomy in 78 infants who died of sudden infant death syndrome (SIDS) to identify such variations. Results showed that in 10 of the 78 infants (13 percent), X-rays of the acromial process had opaque areas that were similar in appearance to what is normally considered a fracture. None of the X-rays were identical, showing a wide variation in development and ossification of the process in these infants. These results indicate that when X-rays of the acromial process are obtained from an infant, they should be examined very carefully before judgments of possible abuse are made. (Consumer Summary produced by Reliance Medical Information, Inc.)

Research, Abnormalities, Diagnosis, Child abuse, Sudden infant death syndrome, Scapula

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