Factors influencing neonatal morbidity in gestational diabetic pregnancy

Article Abstract:

The effects of gestational diabetes (GD), or pregnancy-induced diabetes on neonatal morbidity, was evaluated in 261 women with GD and compared to morbidity in a similar number of newborns of healthy mothers. Perinatal morbidity occurred in 23 percent of the pregnancies of women with GD and 13 percent of the healthy pregnancies. The number of babies who had high birth weights for their gestational age at the time of birth was the same for the two groups. When the infants born to mothers with GD were divided into no-morbidity and morbidity categories it was found that the infants with morbidity had a younger gestational age at birth, higher frequency of cesarean birth, higher maternal pre-pregnancy weight and higher area under the glucose tolerance curve. There was no difference in the third trimester blood sugar levels between the two groups of GD mothers. Further analysis indicated that the strongest determinant of neonatal morbidity was gestational age at birth and, to a lesser degree, maternal pre-pregnancy weight. Researchers concluded that in addition to blood sugar control additional factors effect neonatal outcomes in GD pregnancy.

Patient outcomes, Mortality, Complications and side effects, Infants (Newborn), Newborn infants, Infant mortality, Diabetes in pregnancy, Gestational diabetes, Pregnancy, Complications of, Pregnancy complications

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Cytogenetic findings in 1250 chorionic villus samples obtained in the first trimester with clinical follow-up of the first 1000 pregnancies

Article Abstract:

Chorionic villus sampling (CVS) removes fetal cells early in pregnancy to evaluate the chromosomes for abnormalities. Early diagnosis of fetal abnormalities allows families to decide whether or not to terminate a pregnancy. This large study describes the results of the chorionic villi sampling of 1,250 pregnancies with follow-up on 1,000 pregnancy outcomes. Of 1,205 successful CVS tests, 4.8 percent resulted in pregnancy termination as a result of abnormal findings. There were 2.3 percent false positive results confirmed by the lack of abnormal findings in later fetal tissue analysis. There were false negative findings in one out of the 1,000 pregnancies. Pregnancy loss occurred before 28 weeks gestation in 3.6 percent of all 947 continued pregnancies with normal chromosomal patterns detected by CVS. This may be a result of the general risk of CVS procedures. With obstetricians who had more CVS expertise, pregnancy loss before the twenty-eighth week was 1.3 percent of those showing normal chromosomal patterns.

Research, Diagnosis, Genetic disorders, Cytodiagnosis, Chorionic villus sampling

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The effect of maternal bladder volume on fundal height measurements

Article Abstract:

Fundal height measurement, the size of the uterus during pregnancy, can be made routinely by non-invasive external abdominal manipulation. The measurement can help indicate fetal size, estimate fetal age, predict multiple fetuses and identify possible fetal abnormalities. To determine whether a urine filled bladder can effect the fundal height of a pregnant uterus, 200 non-obese black women, between 16 and 42 weeks of pregnancy, were evaluated before and after urination. Fundal height measurements made with full bladders were greater than those measured after bladder emptying. In order to insure accuracy pregnant women should empty their bladders at least 30 minutes before fundal height measurements are to be taken.

Measurement, Physiological aspects, Urination, Bladder, Uterus, Pregnant, Pregnant uterus

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