Familial urticaria pigmentosa
Article Abstract:
Urticaria pigmentosa is characterized by dermal infiltration of mast cells, which contain histamine, a substance that is responsible for hypersensitivity reactions. There have been sporadic reports of urticaria pigmentosa but familial inheritance of this condition is rarely cited. A case is described of urticaria pigmentosa in three generations of a single family, which suggests it may be an inherited disease. There were five patients with numerous tan skin lesions or macules: a 68-year-old white man, a 34-year-old white woman, a 38-year-old white woman, a seven-year old white girl, and an eight-year-old white boy. Diagnosis of this condition, which depends on a finding of increased numbers of tissue mast cells, was confirmed in all five patients, even though two of the patients lost the characteristic lesions in their early adulthood. This is the second report of familial urticaria pigmentosa in three generations of the same family. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: Archives of Internal Medicine
Subject: Health
ISSN: 0003-9926
Year: 1990
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Physical urticaria: a common misdiagnosis
Article Abstract:
Urticaria, an itching or hives' reaction, seems to be a relatively misunderstood condition. Reported frequencies, descriptions, and possible treatments for various physical urticarias have been presented. Many doctors and patients do not pursue identifying the underlying cause of a urticaria. Therefore, many urticarias may go untreated or unreported. There may be a significant impact on the lifestyle of affected patients while avoiding provoking stimuli. Treatment options include H1 and H2 receptor antagonists and tricyclic antidepressants.
Publication Name: The Nurse Practitioner
Subject: Health
ISSN: 0361-1817
Year: 1996
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A young man with recurrent urticaria
Article Abstract:
Uticaria is a chronic or acute rash-like condition generally related to infections, inhalents, insect bites, drugs, or foods. Antihistamines are usually effective, although an underlying infection or cause must be removed to provide continuing relief. In a case study described, sinusitis played a prominent role in the patient's urticaria.
Publication Name: Physician Assistant
Subject: Health
ISSN: 8750-7544
Year: 1996
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