Gliadel wafers for treatment of brain tumors

Article Abstract:

A biodegradable polymer wafer can safely deliver chemotherapy drugs to the brain in patients with glioblastoma multiforme. Surgery is often used to remove the tumor from the brain. The dime-sized wafer can be placed in the cavity left behind, where the drug carmustine can be released. The wafer eventually disintegrates. Animal studies showed that the concentration of drug in the brain is extremely high, but very little appears in the general circulation. This would spare the patient from side effects. However, the wafers are expensive and do not substantially improve survival rates.

Evaluation, Drug therapy, Glioblastoma multiforme, Drug delivery devices

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Treatment of khat addiction

Article Abstract:

Khat is a bush cultivated in the Middle East and Africa and was found to have strong sympathomimetic effects similar of those of amphetamine. Two cases of khat addiction are discussed. The first patient was a 20-year old white female who chewed khat leaves while the second was the first patient's 26-year old ex-boyfriend who also chewed khat. They were both treated successfully with bromocriptine.

Usage, Complications and side effects, Bromocriptine, Qat

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Caffeine addiction and its effects

Article Abstract:

Ways to identify patients at risk of the side effects of caffeine are proposed, along with methods to help them reduce their intake.

Safety and security measures, Caffeine

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