Plugging the leaks
Article Abstract:
Research has been conducted on the vascular leakage in inflammation which is dependent on neutrophils. The development of the anti-inflammatory drugs with a new action mechanism based on the permeability-enhancing activity produced by neutrophils is described.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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Heparin-binding protein (HBP/CAP37): a missing link in neutrophil-evoked alteration of vascular permeability
Article Abstract:
Research has been conducted on the polymorphonuclear leukocyte. The involvement of the paracrine mechanism in neutrophil-evoked alteration in endothelial barrier function has been investigated and the results are reported.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E
Article Abstract:
Research shows that formation of atherosclerotic lesions by the circulating activated platelets and platelet-leukocyte/monocyte aggregates is due to the platelet P-selectin-mediated delivery of platelet-derived proinflammatory factors onto monocytes/leukocytes and the blood vessel wall in apolipoprotein E deficient mice.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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