Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein
Article Abstract:
Research dedemonstrates that human long-term culture-initiating cells and nonobese diabetic-severe combined immunodeficiency mouse repopulating cells are expanded greater than 20- and 2.5-fold, respectively, when cultured on stromal cells genetically programmed to secrete HOXB4 homeoprotein.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
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Not asleep, not quite awake
Article Abstract:
Narcoleptic individuals experience episodes of cataplexy, which is a sudden complete loss of skeletal muscle tone. During cataplectic episodes, the individuals are awake, aware of their environment and otherwise conscious.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
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