Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury
Article Abstract:
Research reveals that mucin-like domain of the Ebola virus glycoprotein is responsible for the viral pathogenicity and for hemorrhage during infection. Data indicate that the glycoprotein causes these cytotoxic effects in human endothelial cells via a serine-threonine-rich mucin-like domain.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Heme oxygenase-1 protects against vascular constriction and proliferation
Article Abstract:
Research has been conducted on the heme oxygenase, an inducible protein activated by the oxidant stress in the systemic inflammatory conditions. Results indicate that this oxygenase reduces vasoconstriction and inhibits cell proliferation during vascular injury.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
NIH research on obesity and type 2 diabetes: Providing the scientific evidence base for actions to improve health
Article Abstract:
The US National Institutes of Health (NIH) aims at developing strategies for prevention and treatment of various diseases and also provides several scientific evidence for the implementation of actions to cure diseases like obesity and type 2 diabetes. NIH supports many basic and clinical research partnerships in obesity to achieve this goal and also seeks various other researches to improve the health of the whole nation.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. Gene silencing in cancer in association with promoter hypermethylation
- Abstracts: Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and those without HIV infection
- Abstracts: Matrilysin (matrix metalloproteinase 7) in parturition, premature rupture of membranes, and intrauterine infection
- Abstracts: A study of the relationship between placenta growth factor and gestational age, parturition, rupture of membranes, and intrauterine infection
- Abstracts: A simplified index of the plasma sodium threshold for arginine vasopressin secretion -- morning fasting, euhydrated sodium levels