A simplified index of the plasma sodium threshold for arginine vasopressin secretion -- morning fasting, euhydrated sodium levels

Article Abstract:

Researchers describe a simple method of determining the osmotic threshold for arginine vasopressin secretion in pregnant women. During pregnancy, this threshold seems to be adjusted to account for a 30% to 50% increase in blood volume.

Pregnancy, Vasopressin, Vasopressins

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Mathematic modeling of human amniotic fluid dynamics

Article Abstract:

A mathematical model of the production and uptake of amniotic fluid produced results compatible with the known data. Using data from human and animal studies on the composition of amniotic fluid, its production via urine and lung liquid secretion, and its uptake via swallowing and possibly diffusion into blood, researchers developed a mathematical model of amniotic fluid dynamics. The model explained the decrease in amniotic fluid towards the end of pregnancy as being due to increased swallowing and accurately predicted the build-up of amniotic fluid resulting from a congenital anomaly preventing swallowing.

Fetus, Deglutition

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Human amniotic fluid mathematical model: determination and effect of intramembranous sodium flux

Article Abstract:

Physiologic, mathematical, and experimental models of amniotic fluid dynamics during pregnancy indicate that fetal swallowing eliminates excess fluid in early pregnancy. After 28 to 32 weeks' gestation, amniotic fluid flow across the amniotic membranes maintains an appropriate amniotic fluid volume. Mass balance equations predict that sodium moves preferentially into the amniotic fluid, and variations of 5% are sufficient to produce large changes in amniotic fluid volume by dramatically altering fluid balance.

Oligohydramnios, Sodium in the body, Sodium (Nutrient)

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