In situ human papillomavirus (HPV) genotyping of cervical intraepithelial neoplasia in South African and British patients: evidence for putative HPV integration

Article Abstract:

Over the past decade, more than 60 different types of human papillomavirus (HPV) have been identified. These different types can be distinguished from one another by examining their DNA (the genetic material). HPV type 6, 11, 42, 43 and 44 are most commonly found in warts that grow on the genital organs (genital condylomata) and in low-grade cervical dysplasia (the growth of abnormal cells in the cervix, which can lead to cancer). Types 16, 18, 31, 33, 35, 45, 51, 52 and 56, on the other hand, are found in high-grade cervical dysplasia. It has been reported that the incidence of cervical cancer is increasing in South Africa. Since there have not been any studies on the prevalence of the different types of HPV related to cervical dysplasia in South Africa, a study was performed to address this issue. Seventy-two South African women and 73 British women with cervical dysplasia were tested for HPV infection. HPV was found in samples of cervical tissue from 68 percent of the British women and 50 percent of the South African women. HPV 16 was the most common type found. It appeared in 68 percent of the British and 44 percent of the South African samples that were positive for HPV. HPV 33 and 35 were found in 16 percent of the British and 36 percent, respectively, of the South African samples that tested positive for HPV. The was no relationship between age and the type of HPV infection in either population. These findings indicate that infection with different types of HPV varies from one geographical region to another, and that the minor types of HPV (33 and 35) are more common in South Africa. (Consumer Summary produced by Reliance Medical Information, Inc.)

Condyloma acuminatum, Genital warts, Papillomavirus infections, Cervix dysplasia

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Onchocerciasis and epilepsy: a matched case-control study in the Central African Republic

Article Abstract:

Epileptic episodes may not be associated with onchocerciasis, a parasitic infestation causing river blindness. Researchers examined the rate of onchocerciasis among 187 epileptics and 374 persons without epilepsy in the Central African Republic. There was no difference between cases and controls, since more than a third of both the epileptics and non-epileptics had onchocerciasis. These results stand in contrast to other findings linking epilepsy and onchocerciasis.

Central African Republic, Complications and side effects, Risk factors, Epilepsy, Onchocerciasis

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Perceived health status in African American and Caucasian Men 40 to 70 years old

Article Abstract:

Issues are presented concerning the evaluation of 2,001 Caucasian and African American men taking part in screening for prostate cancer to determine the relationship between demographic variables and health status.

Health aspects, Prostate cancer, Health, Caucasian race, Whites, African American men

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