In vitro anti-Toxoplasma gondii antibody production by peripheral blood mononuclear cells in the diagnosis and the monitoring of toxoplasmic encephalitis in AIDS-related brain lesions
Article Abstract:
Measuring the amount of antibody against Toxoplasma gondii in blood cells can be an accurate diagnostic technique for detecting this parasite in HIV patients. The parasite often affects the brain, and this diagnostic technique can also be used to monitor the response to treatment.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2000
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Detection and Enumeration of circulating HIV-1-specific memory B cells in HIV-1-infected patients
Article Abstract:
The effect of Memory B cells throughout the body of the HIV-1-infected patients is described. The effect of HIV-1-specific resting memory cells which circulate in the blood of AIDS patients can be quantified by their anti-HIV-1 antibody secretion after strong B cell polyclonal stimulation.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2004
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Detection and enumeration of HIV-1-producing cells by ELISPOT (Enzyme-Linked ImmunoSpot) assay
Article Abstract:
An enzyme-linked immunoassy called ELISPOT appears capable of decting individual immune cells that are producing HIV. HIV infects immune cells called CD4+ T cells, monocytes and macrophages and then uses the cell to produce more HIV. Researchers used ELISPOT to measure HIV-producing cells in blood samples and a human T-lymphoblastoid cell line that were infected with HIV. The assay showed that 11% to 24% of the blood cells and 5% to 9% of the cells in the cell line were producing HIV.
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1999
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