Prevalence of multiple dideoxynucleoside analogue resistance (MddNR) in a multicenter cohort of HIV-1-infected Italian patients with virologic failure
Article Abstract:
About 3% of all HIV patients in Italy may be infected with a strain of HIV that is resistant to more than one nucleoside reverse transcriptase inhibitor. This was the conclusion of a study of 177 HIV patients who did not respond to combination drug therapy.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2000
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Increasing prevalence of non-clade B HIV-1 strains in heterosexual men and women, as monitored by analysis of reverse transcriptase and protease sequences
Article Abstract:
The presence of non-clade B HIV strains is increasing in Europe, and women and heterosexuals are at highest risk. Although clade B strains are the predominant strain in Europe, Australis, and the US, this could change, according to Italian researchers.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
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The calculated genetic barrier for antiretroviral drug resistance substitutions is largely similar for different HIV-1 subtypes
Article Abstract:
The genetic barrier between subtypes are compared using some 2000 HIV-1 sequences (>600 of non-B subtype) isolated from anti-retroviral-naive patients in Europe. Based on the calculated genetic barrier, the rate of drug resistance development may be similar for different HIV-1 subtypes.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
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