Influenza immunization for children

Article Abstract:

It may be premature to recommend influenza vaccination for all children but those at high risk of contracting influenza may benefit. Although there already are effective influenza vaccines, studies have shown that few children are vaccinated. A 1998 study found that a live attenuated influenza vaccine was 93% effective in a group of children. The vaccine was administered intranasally, which would eliminate the need for multiple injections. However, studies have shown that vaccination of high-risk adults is the most cost-effective use of influenza vaccine.

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Cytomegalovirus infection and HIV-1 disease progression in infants born to HIV-1-infected women

Article Abstract:

Cytomegalovirus (CMV) infection in HIV-infected infants appears to increase the rate of HIV disease progression and increase the risk of death. Researchers studied 75 infants with HIV and 365 uninfected infants born to HIV-infected mothers. At birth, about 4.5% of the children were infected with CMV. By six months of age, 40% of HIV-infected infants had CMV infection as well, while only 15% of HIV-negative infants had CMV. By 18 months of age, 53% of coinfected infants had died, while 22% of infants infected with only HIV had died.

United States, Health aspects, Development and progression, HIV infection in children, Pediatric HIV infections, Cytomegalovirus infections

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Is it time to give influenza vaccine to healthy infants?

Article Abstract:

More research is needed before influenza vaccination of infants can be recommended. Two 1999 studies showed that influenza causes increased hospitalization rates among children during years when the virus is circulating. However, respiratory syncytial virus also causes respiratory infection in young children and the effect of influenza virus may be hard to distinguish. Vaccines are not without side effects and adding influenza vaccine to the extensive list of vaccines most children already receive might not be cost-effective.

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