Disease, drug response linked to loss of gain of big DNA chunks in genome

Article Abstract:

A relatively new field of genetic study shows that copy number variations (CNVs) in DNA bases could be involved with disease occurrence and drug response, providing insights into human genome evolution. A specific link between a CNV and disease was found when researchers discovered that resistance to infection by HIV is determined in part by multiple copies of the gene that encodes CCL3L1, a protein that blocks the binding of HIV to host cells.

HIV infection, HIV infections, Nucleotide sequence, Base sequence, Genetic research, Genetic variation

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Genetic flaw linked to early heart disease: Association with osteoporosis also found

Article Abstract:

Researchers have found that the mutation of the gene that codes for low-density lipoprotein (LDL) receptor-related protein 6 (LRP6) might provide clues to common abnormalities underlying altered glucose homeostasis, elevated blood pressure, dyslipidemia and low bone density. They are trying to explore the relationship between coronary artery disease and osteoporosis.

Risk factors, Heart diseases, Osteoporosis, Low density lipoprotein receptors

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