C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

Article Abstract:

Blood levels of C-reactive protein (CRP) can be used to diagnose cardiovascular disease in women. This protein is a marker of inflammation in the body. In a study of 28,263 healthy postmenopausal women, CRP was the strongest predictor of a future heart attack or stroke. Women with the highest blood CRP levels had 4 times the risk of a heart attack or stroke. Blood levels of amyloid A, homocysteine, total cholesterol, LDL and HDL cholesterol, and apolipoprotein B-100 were also important. Elevated blood lipid levels and markers of inflammation were better predictors than blood lipid levels alone.

Diagnosis, Inflammation, Inflammation mediators, C-reactive protein

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A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women

Article Abstract:

A trial was designed to evaluate the lowest dose of aspirin that would have a cardio protective effect, while minimizing gastrointestinal side effects through the use of a low dose and alternate-day administration. It was observed that aspirin lowered the risk of stroke without affecting the risk of myocardial infarction or death from cardiovascular causes, leading to a nonsignificant finding with respect to the primary end point.

United Kingdom, Science & research, Research, Women, Clinical trials, Women's health

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Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease

Article Abstract:

Long-term supplementation of beta carotene apparently had no effect on preventing cancer, heart disease, or death. Beta carotene is a dietary source of vitamin A found in green and yellow vegetables. Researchers observed the rate of cancer and heart disease as well as death from all causes among 22,071 male physicians over a period of 12 years. A total of 11,036 men took a beta carotene supplement of 50 milligrams every other day, while 11,035 men took a placebo (the control group). The beta carotene group maintained a compliance rate of 78%. There was virtually no difference between groups with respect to any type of cancer or heart disease. For example, 386 cancer deaths occurred in the beta carotene group compared to 380 cancer deaths in the control group. There were also no overall mortality group differences, smoker versus non-smoker effects, or major side effects in either group.

Health aspects, Physicians, Medical professions, Cancer, Cancer prevention, Beta carotene

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