Maintenance therapy with certolizumab pegol for Crohn's disease
Article Abstract:
A randomized trial involving maintenance and withdrawal therapy with certolizumab pegol in patients with moderate-to-severe Crohn's disease is presented. Results show that patients who had a response to induction therapy with 400 mg of certolizumab pegol are more likely to have a maintained response and a remission at 26 weeks with continued treatment than with a switch to placebo.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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Certolizumab pegol for the treatment of Crohn's disease
Article Abstract:
A study evaluates the efficacy of certolizumab pegol in adults with moderate-to-severe Crohn's disease. Findings suggest that induction and maintenance therapy with certolizumab pegol is associated with a modest improvement in response rates, as compared with placebo, but there is no significant improvement in remission rates.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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Natalizumab induction and maintenance therapy for Crohn's disease
Article Abstract:
Two controlled experiments are carried out to examine natalizumab as induction and maintenance treatments in patients suffering from active Crohn's disease. Findings indicate that for Crohn's disease, induction therapy with natalizumab produced small insignificant improvements in response and remission rates.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
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