Major basic protein as a marker of malignant potential in trophoblastic neoplasia
Article Abstract:
Differences in the level of pregnancy-associated major basic protein (pMBP) as measured in pregnancy tests appear to be useful in distinguishing a normal pregnancy from cancerous and non-cancerous growths. Blood levels of pMBP were compared in women with normal pregnancies, cancerous and non-cancerous growths arising from abnormally developed pregnancies, and in non-pregnant women. Women with non-cancerous growths had higher pMBP levels than those with normal pregnancies. Non-pregnant women had higher pMBP levels than those with cancerous growths. Women with cancerous and non-cancerous growths had significantly different pMBP levels.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1996
User Contributions:
Comment about this article or add new information about this topic:
Persistent low levels of human chorionic gonadotropin: a premalignant gestational trophoblastic disease
Article Abstract:
Women who have persistent low blood levels of human chorionic gonadotropin even though they are not pregnant may have a precancerous condition called premalignant gestational trophoblastic disease. Normally, human chorionic gonadotropin is only produced during pregnancy. However, it can also be produced by embryonic cells that become cancerous instead of growing into a human baby.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
Expressions of proliferation markers (Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizer regions) and of p53 tumor protein in gestational trophoblastic disease
Article Abstract:
Various biological markers of cell proliferation could be used to diagnose gestational trophoblastic disease. These markers include Ki-67, proliferating cell nuclear antigen, and silver-staining nucleolar organizing regions. Gestational trophoblastic disease is a tumor caused by abnormal growth of embryonic fetal membranes.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Body exhibitions are an essential adjunct to health education. This one's personal
- Abstracts: Intake and sources of alpha-linolenic acid in Dutch elderly men. Associations of alpha-linolenic acid and linoleic acid with risk factors for coronary heart disease
- Abstracts: The immunopathogenesis of gastrointestinal and hepatobiliary diseases. Prospects for Research in Inflammatory Bowel Disease
- Abstracts: New studies say viral burden tops CD4 as a marker of HIV disease progression
- Abstracts: Brief report: a familial syndrome of arterial dissections with lentiginosis. Spontaneous disection of the carotid and vertebral arteries