Meal frequency; does it determine postprandial lipaemia?

Article Abstract:

Fasting or postprandial lipids of non-esterified fatty acids, glucose- dependent insulinotropic polypeptide levels, glucagon-like peptide, glucose, triacylglycerol, and immunoreactive insulin are unaffected after a two week adherence to a nibbling or gorging diet. Similar food content and nutrient value of the diets resulted in the nibbling diet showing no beneficial effects, unlike in other studies. The levels of postheparin lipase activity, low density lipoprotein-cholesterol concentrations, and fasting total also remain similar. Gorging diet, however, raises the concentration of high density lipoprotein-cholesterol.

Analysis, Hormones, Lipids, Food consumption, Lipids in nutrition

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Postprandial lipid and hormone responses to meals of varying fat contents: modulatory role of lipoprotein lipase?

Article Abstract:

Analysis of the hormone and substrate changes with variation in fat proportion in 10 healthy subjects using pre- and postprandial blood samples reveals a steady increase in lipaemic response to fat load while differences between postprandial plasma triacylglycerol amount in the 20 and 40 g fat meals were less significant than expected. Glucose-dependent insulinotrophic polypeptide may control lipoprotein lipase increase with increasing fat content and play a significant role in lipoprotein homeostatis circulation.

Dietary fat

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The quantitation of lipoprotein lipase mRNA in biopsies of human adipose tissue, using the polymerase chain reaction, and the effect of increased consumption of n-3 polyunsaturated fatty acids

Article Abstract:

The reverse transcriptase PCR method is sufficiently specific and sensitive to detect lipoprotein lipase in adipose tissue biopsies taken from free-living volunteers of normal body weight. There is evidence that changes in lipoprotein lipase expression are connected with long-term changes in plasma triacylglcerol levels. This in turn indicates that factors contributing to attenuation in lipoprotein lipase expression could play a significant role in determining raised fasting and postprandial triacylglcerol.

Causes of, Coronary heart disease

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