Molecular genetics of lung cancer

Article Abstract:

This review surveys the various ways the pulmonary cells can become susceptible to cancerous state from genetic, molecular changes to environmental influence. Research indicates that development of lung cancer involves sequential accumulation of specific genetic and morphologic changes in the normal lung epithelial cells. Furthermore, evasion of apoptosis and senescence, angiogenesis, and epigentic inactivation of genes via DNA methylation also predispose normal cells to cancerous state.

Australia, Japan, Influence, Environmental aspects, Lung cancer, Oncogenes, Gene silencing

---

Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans

Article Abstract:

This review examines the feasibility of using calorie restiction treatment mode in order to prevent chronic disease prevention and to promote healthy aging in humans. Research illustrates many beneficial effects of calorie restriction including its positive effect in the reduction of insulin-like growth factor-1 involved in cancer development. Furthermore, calorie restiction enhances apoptosis and dcreases DNA synthesis leading to a reduction in preneoplastic lesions.

Calories, Prevention, Causes of, Chronic diseases, Reducing diets, Insulin-like growth factor 1, Insulin-like growth factor I, Active oxygen, Apoptosis

---

Genetics and arrhythmias

Article Abstract:

This review describes the research advances in the pathophysiological mechanisms of monogenic arrhythmic diseases since the discovery of the first gene responsible for cardiac arrhythmia. These genes encode ion channel proteins that are affected in arrhythmia patients. Future research will benefit from genotyping and sequencing these channelopathy genes.

Analysis, Heart diseases, Sudden death, Ion channels, Heredity, Arrhythmia, Genes

Similar abstracts:

• Abstracts: Long-term risk of colorectal cancer after excision of rectosigmoid adenomas. Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome
• Abstracts: A critique of the rationale for cancer treatment with coffee enemas and diet. Multistate outbreaks of Salmonella infections associated with raw tomatoes eaten in restaurants - United States, 2005-2006
• Abstracts: Selecting compression hosiery. The identification and diagnosis of malignant leg ulcers. Comparative benefits
• Abstracts: Skin test responses as predictors of tuberculosis infections and of progression in HIV-infected persons. Trimethoprim-sulfamethoxazole induces reversible hyperkalemia
• Abstracts: Skin test responses as predictors of tuberculosis infections and of progression in HIV-infected persons. part 2

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.