Mortality from breast cancer after irradiation during fluoroscopic examinations in patients being treated for tuberculosis

Article Abstract:

High doses of radiation from X-rays and gamma rays are associated with an increased risk of breast cancer. There is some concern over the risk of low-dose radiation from mammography, the use of X-rays to visualize breast tissue and breast cancer. It is difficult to correctly assess the risk of developing cancer by studying low doses of radiation. Instead, models based on high-dose radiation effects are used to estimate and predict relationships between radiation dose and cancer development. Most studies on the effects of radiation are done on women who survived the radiation of the atomic bombs in Japan. A single heavy exposure to radiation is not useful in predicting the effects of a series of radiation exposures from medical diagnostic procedures. Women with tuberculosis, a bacterial disease affecting lung tissue, were constantly exposed to radiation from repeated X-ray evaluation from 1930-1952 in a sanatorium in Nova Scotia. The breast cancer rate was found to be high in the same area. An examination of 31,710 women was performed to evaluate the effects of this radiation on later breast cancer development. It was found that the more radiation a women was exposed to, the higher the incidence of breast cancer, particularly those irradiated between the ages of 10 and 14. The risk of breast cancer decreased sharply with increasing age in the irradiated study group. Using this model, it can be assumed that this decreased risk for breast cancer in older women supports the argument for routine mammography screening. The benefits of early detection seem to outweigh the risks of radiation-induced breast cancer.

Physiological aspects, Radiation, Tuberculosis, Cancer

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Cohort studies of fat intake and the risk of breast cancer - a pooled analysis

Article Abstract:

Consumption of dietary fat does not appear to be related to the risk of breast cancer. Studies on the relationship between fat intake and breast cancer have produced contradictory results. Researchers reanalyzed data from seven such studies including information on 4,980 women. The risk of developing breast cancer was similar in the women who consumed the most fat and those who consumed the least fat. The risk of breast cancer also among the highest and lowest consumers of cholesterol and saturated, monounsaturated, and polyunsaturated fats. The risk was also unrelated to the percentage of energy intake that came from fat. These results did not change with an adjustment for errors in measuring nutrient consumption.

Dietary fat

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Alcohol and breast cancer in women: a pooled analysis of cohort studies

Article Abstract:

Women who drink alcohol may want to limit their intake in order to reduce their risk of breast cancer. Researchers reviewed six studies covering 322,647 women that analyzed the link between food intake and breast cancer. Women who drank two to five drinks a day had a 40% greater risk of breast cancer than non-drinkers. Intakes above that amount do not seem to increase the risk. The type of alcoholic beverage consumed had no effect on risk.

Women, Drinking of alcoholic beverages, Drinking (Alcoholic beverages), Alcohol use

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