Mycobacterial virulence and specialized secretion: Same story, different ending
Article Abstract:
The dissection of the components of a newly discovered secretion system conserved among gram-positive bacteria has revealed a unique Mycobacterium tuberculosis-specific signal for export of bacterial proteins into the host. The data has provided an explanation of how Mycobacterium tuberculosis has evolved a novel use for a conserved secretory apparatus.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
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Identification of a hormonal basis for gall bladder filling
Article Abstract:
The way in which fibroblast growth factor-15, a hormone created by the distal small intestine in response to bile acids is needed for gall bladder filling is described. It is suggested that the postprandial timing mechanism is required that controls gall bladder motility as the filling of the gall bladder is actively regulated by an endocrine pathway.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
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Streptococcus moves inward
Article Abstract:
A wide spectrum of group A streptococcal (GAS) causes mysterious and uncomplicated diseases from benign strep throat to 'flesh-eating' wound infections. The GAS virulence depends on arrays of secreted and surface proteins that retard innate defenses, mimic host macromolecules and derange adaptive immunological responses.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
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