New neuromuscular blocking drugs

Article Abstract:

Pharmaceutical companies have yet to devise a neuromuscular blocking drug that takes effect quickly, lasts a fairly long time, has few side effects and is rapidly secreted by the body. Neuromuscular blocking drugs act by blocking the nerve impulse that makes a muscle contract. Several drugs have been developed for different types of medical interventions, including tracheal intubation, surgery, mechanical ventilation and treatment of burn patients. Because the drugs can affect other neurotransmitter receptors, they can affect the heart and other organs. They should be used with special care in infants and the elderly and in patients with kidney, liver, heart and neuromuscular diseases.

Physiological aspects, Neuromuscular blocking agents

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Myocardial bridging in children with hypertrophic cardiomyopathy - a risk factor for sudden death

Article Abstract:

Myocardial bridging can be a serious complication of hypertrophic cardiomyopathy in children. Hypertrophic cardiomyopathy is a heart disease characterized by an enlarged heart. Myocardial bridging occurs when the enlarged heart compresses one of the coronary arteries. In a study of 36 children with hypertrophic cardiomyopathy, 28% experienced myocardial bridging. These children were more likely to have chest pain, cardiac arrest, severe arrhythmias, and inability to exercise for long periods of time. They also had lower five-year survival rates.

Cardiomyopathy, Hypertrophic, Sudden death, Hypertrophic cardiomyopathy

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Class of antiretroviral drugs and the risk of myocardial infarction

Article Abstract:

Study reveals that longer exposure to protease inhibitors increases the risk of myocardial infarction in patients however no association was found between use of nonnucleoside reverse-transcriptase inhibitors and risk of myocardial infarction.

Heart attack, Antiviral agents, Antiretroviral agents, Clinical report

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