Novel targeted cancer drugs highlighted
Article Abstract:
Continued search for effective treatments for cancer helped the scientist investigating the novel targeted therapies in reporting results of several early trials at the meeting of the American Society of Clinical Oncology. It is reported that an agent that binds to receptors on cancer cells that trigger apoptosis, or cell death, halted cell growth in more than half of the patients whose tumor could be assessed in the first phase of the trial.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
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Study reveals mitochondrial role in aging
Article Abstract:
Experiments that caused mice to quickly develop characteristics of premature aging reveal that mutations in mitochondrial DNA may play a key role in growing old. The findings demonstrate that an accumulation of genetic mutations in mitochondria sets off a cascade of signals that causes programmed cell death, or apoptosis that results in loss of irreplaceable cells and progression of aging.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
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Mitochondrial defects may play role in the metabolic syndrome
Article Abstract:
Genetic components play a role in the metabolic syndrome and scientists have identified a potential genetic cause for some individuals with the condition. The factors characteristic of the syndrome are discussed.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
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