Oats and celiac disease
Article Abstract:
A 1995 study suggests that people with celiac disease who are on gluten-free diets may eat oats without aggravating the disease. Celiac disease involves the breakdown of the intestinal lining and is usually treated successfully with a gluten-free diet, which is difficult to maintain. For approximately 30 years researchers have produced conflicting studies about whether or not people with celiac disease can tolerate oats. In the 1995 study, 50 adults with recently diagnosed celiac disease and 52 with the disease in remission were put on gluten-free diets with or without oats. During follow-up periods of 6 and 12 months all but one of the people experienced remission. Several earlier studies suggested the aggravating agent in wheat products is a peptide in the proteins gliadin and avenin. Oats contain avenin, but probably in small quantities.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1995
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Liver disease in pregnancy
Article Abstract:
Liver disease during pregnancy is rare, but it can be serious and even lead to death. Cholestatic liver diseases are characterized by abnormal bile secretion and include hyperemesis gravidarum, intrahepatic cholestasis of pregnancy, adverse drug effects, primary biliary cirrhosis and the Dubin-Johnson syndrome. Diseases that affect the liver itself include viral hepatitis, acute fatty liver of pregnancy, preeclampsia and eclampsia and the HELLP syndrome. The symptoms of liver disease include itching, jaundice, nausea and vomiting, upper abdominal pain and low blood platelet counts.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
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Lymphocyte-mediated cytolysis and disease
Article Abstract:
Research is shedding light on the mechanisms by which white blood cells called lymphocytes kill pathogenic organisms and also how they contribute to autoimmune diseases. Lymphocytes contain a protein called perforin because it can create holes in the membrane of foreign cells, which eventually kills them. Lymphocytes also contain enzymes called granzymes, which break down proteins. These chemicals are used to destroy bacteria and viruses, but can also damage normal tissues when the mechanism goes awry.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
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