Pancreatic endocrine tumors - the search goes on

Article Abstract:

Until recently, no single imaging method has been completely effective in diagnosing pancreatic tumors. A recent study found that 32 of 39 tumors identified at surgery could be detected beforehand by endoscopic ultrasound. However, its success in detecting endocrine tumors outside the pancreas was not tested. Many gastrinomas - tumors that secrete the hormone gastrin - are located in the duodenum beneath the lining of the intestine. They are hard to detect by most imaging techniques, and as many as 55% are malignant. Endoscopic ultrasound may also be less effective at detecting tumors in the tail of the pancreas. Many gastroenterologists will have to be trained to perform this technique. Endoscopic ultrasound may replace the use of arteriography in detecting pancreatic tumors, but if it fails, the tumor can usually be localized using ultrasound during surgery.

Editorial, Evaluation

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Localization of pancreatic endocrine tumors by endoscopic ultrasonography

Article Abstract:

Endoscopic ultrasonography may be more effective in detecting pancreatic tumors than conventional ultrasonography or computed tomography. In 37 patients with the signs and symptoms of pancreatic tumors, abdominal ultrasonograms and CT scans had been negative. But endoscopic ultrasonography detected 82% of the tumors that were subsequently found at surgery. Endoscopic ultrasonography also correctly estimated the size of the tumors within two millimeters of that found during surgery. Twenty-two patients also underwent angiography, but this imaging technique only detected 27% of the tumors. In 19 patients with no signs and symptoms of pancreatic tumors, endoscopic ultrasonography correctly identified 18 as being disease-free. Surgeons found that the remaining patient had lymph nodes in the pancreas, but no sign of a tumor.

Usage

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Endoscopic ultrasound added to mediastinoscopy for preoperative staging of patients with lung cancer

Article Abstract:

A study is conducted to investigate the additional value of transesophageal ultrasound-guided fine-needle aspiration (EUS-FNA) to mediastinoscopy in the preoperative staging of patients with non-small cell lung cancer. Findings suggest that when EUS-FNA is added to mediastinoscopy it improves the preoperative staging of lung cancer.

United States, Care and treatment, Analysis, Preoperative care, Lung cancer, Mediastinoscopy

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