Parkinson's disease

Article Abstract:

Research on Parkinson's disease is increasing the list of drugs and other treatments that may be effective. Parkinson's disease is caused by damage to certain areas of the brain that result in tremors, rigidity and difficulty moving. Levodopa is the most commonly used drug and should be started early. It does have side effects and as the disease advances, many patients may have "off" days when they do not respond to the drug. Other drugs include bromocriptine, pergolide, selegiline, clozapine and risperidone. Surgery and electrical stimulation of affected brain areas can be effective treatments.

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Subthalamic stimulation for Parkinson's disease -- living better electrically?

Article Abstract:

Electrical stimulation of a region of the brain called the subthalamic nucleus may benefit some patients with Parkinson's disease but should not be used as a substitute for medications. A 2003 study of 49 patients found that some symptoms improved with this treatment, but it did not prevent other symptoms from developing. The treatment involves placing electrodes inside the brain, which is not a simple procedure and may not be suitable for elderly patients.

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Five-year follow-up of bilateral stimujlation of the subthalamic nucleus in advanced Parkinson's disease

Article Abstract:

Electrical stimulation of a region of the brain called the subthalamic nucleus may benefit some patients with advanced Parkinson's disease, according to a study of 42 patients. This treatment involves surgically implanting electrodes in the patient's brain, as well as a small electrical generator underneath the skin of the skull. The treatment did not prevent their symptoms from getting worse but improved some types of muscle function.

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