Peritoneal reaction resulting from iodinated contrast material: comparative study
Article Abstract:
The ability to visualize internal organs by X-ray often employs contrast materials (dyes) which block the passage of X-rays and can, therefore, be detected. This study examines various contrast materials which have been used for visualization of the uterus and fallopian tubes (hysterosalpingography) and the ability of these materials to induce inflammatory reactions in the lining of the abdominal cavity (peritoneum). This pathologic process is possible since the fallopian tubes are open conduits from the uterus into the peritoneal cavity. This study models the human situation by the use of direct injections of contrast materials into the peritoneal cavity of guinea pigs. The inflammatory response of the animals was examined at one day, one week and one month following the injection. The degree of inflammation produced by various materials was documented. One contrast material consistently failed to induce pathologic changes (iothalamate meglumine). Contrast materials which induced pathologic changes produced striking inflammatory responses at one month. The sole use of meglumine-based water-soluble ionic contrast material for hysterosalpingography is recommended on the basis of these experiments.
Publication Name: Radiology
Subject: Health
ISSN: 0033-8419
Year: 1989
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Transient global amnesia associated with cerebral angiography performed with use of iopamidol
Article Abstract:
In angiography, a catheter (a tube) is placed into any of the body's arteries and a dye which can be detected by X-ray is injected. This process allows the radiologist to follow the filling and circulation of blood through the vessel system. This paper presents a case of two patients who were hospitalized and underwent a procedure to demonstrate the vessels of their brain (cerebral angiography) with the use of the dye (or contrast), iopamidol. Iopamidol is an uncharged, or non-ionic, contrast material which belongs to a new generation of such materials that were introduced during the 1980s. One advantage of this material has been the reduction of temporary and generalized loss of memory (transient global amnesia). This case report documents transient global amnesia following cerebral angiography with the nonionic, iopamidol contrast agent. The problem is self-limiting and the amnesia, accompanied by headache, and other visual problems, disappeared over the next five days. The physiologic mechanism of this process is unknown.
Publication Name: Radiology
Subject: Health
ISSN: 0033-8419
Year: 1989
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Assessment of resident competency in the performance of sonohysterography: does the level of training impact the accuracy?
Article Abstract:
The study focuses on evaluating the true-positive rates by level of training of the operator and on determining whether the accuracy of the procedure differed by the level of education after formalized training. The results indicate that the true-positive rates for saline hysterography are comparable among different provider levels.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2004
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