Plasma concentration of lipoprotein(a) and the risk of future stroke
Article Abstract:
Blood levels of lipoprotein(a) (Lp(a)) do not appear to be related to the risk of stroke. Researchers took blood samples from 14,916 healthy middle-aged men and followed the men for an average of 7.5 years to study the relationship between Lp(a) and stroke. At follow-up, 198 men had suffered a stroke. The median Lp(a) concentration at the beginning of the study were 8.88 milligrams per deciliter (mg/dL) in men who had suffered a stroke and 8.55 mg/dL in the other men. Most men in both groups had Lp(a) levels below 20 mg/dL. Men did not have an increased risk of stroke even if their Lp(a) levels were 25%, 50%, 75%, or 95% higher than the median of those who did not develop a stroke. Lp(a) levels were not related to the risk of stroke in men who had high blood cholesterol or in men who suffered a stroke caused by a blood clot rather than a brain hemorrhage.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1995
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Lipoprotein(a), measured with an assay independent of apolipoprotein (a) isoform size, and risk of future cardiovascular events among initially healthy women
Article Abstract:
A study was conducted to determine the association of lipoprotein(a) levels, measured with an assay independent of apolipoprotein(a) isoform size, with the incidence of future cardiovascular events. It was found that in the cohort of initially healthy women, extremely high levels of lipoprotein(a), measured with an assay independent of apolipoprotein(a) isoform size, were associated with increased cardiovascular risk, particularly in women with high levels of LDL-C.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
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Novel Risk Factors for Systemic Atherosclerosis: A Comparison of C-Reactive Protein, Fibrinogen, Homocysteine, Lipoprotein(a), and Standard Cholesterol Screening as Predictors of Peripheral Arterial Disease
Article Abstract:
Out of 11 potential risk factors for atherosclerosis, only elevated C-reactive protein levels and low levels of HDL, or 'good' cholesterol in relation to total cholesterol appear to be serious risk factors. The other 9 risk factors included total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides, homocysteine, lipoprotein(a), fibrinogen, and apolipoproteins (apo) A-I and B-100.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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