The relationship between neurally mediated hypotension and the chronic fatigue syndrome
Article Abstract:
Chronic fatigue syndrome may be linked to neurally mediated hypotension. Neurally mediated hypotension is a fall in blood pressure caused by an abnormal cardiovascular reflex, and is characterized by dizziness, fainting, and blurred vision. Researchers compared symptoms and response elicited by upright tilt-table testing in 23 people with chronic fatigue syndrome and 14 people who did not have the condition (the control group). Twenty-two patients with chronic fatigue syndrome reacted abnormally to the upright tilt compared to four people in the control group. Sixty-one percent of the participants with chronic fatigue syndrome said they avoided salt in their diets, however, salt should not be restricted. The chronic fatigue syndrome group was offered treatment options which included fludrocortisone, beta-adrenergic blocking agents, and disopyramide. Nine of these people recovered fully after treatment.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1995
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Low-Dose Hydrocortisone for Treatment of Chronic Fatigue Syndrome
Article Abstract:
Hydrocortisone may be beneficial in some patients with chronic fatigue syndrome. Researchers randomly assigned 56 women and 14 men with chronic fatigue syndrome to take oral hydrocortisone or a placebo for about 12 weeks. Two-thirds of the patients taking hydrocortisone experienced an improvement in symptoms compared to half of those taking a placebo. However, the drug suppressed the adrenal glands in 12 of the patients in the hydrocortisone group. This is a fairly serious side effect and may limit the drug's usefulness in these patients.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Fludrocortisone Acetate to Treat Neurally Mediated Hypotension in Chronic Fatigue Syndrome: A Randomized Controlled Trial
Article Abstract:
Fludrocortisone acetate does not appear to be effective in treating low blood pressure in patients with chronic fatigue syndrome. Other studies have shown that treating low blood pressure can improve symptoms in chronic fatigue syndrome, but a study of 83 patients did not confirm those results.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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