Polymerase chain reaction search for viral etiology of vulvar vestibulitis syndrome

Article Abstract:

Human papillomavirus may be associated with the development of vulvar vestibulitis syndrome. The principal symptom of vulvar vestibulitis is pain around the vaginal opening with intercourse. Researchers analyzed biopsy specimens from 86 women with severe problems for the presence of herpes simplex virus, cytomegalovirus, and human papillomavirus and compared results with 25 healthy women having episiotomy repair after childbirth or surgery for other purposes. Human papillomavirus was found in over half of the women with vestibulitis but in only one of the healthy women. The other two viruses were not found in either group.

Papillomaviruses, Papillomavirus, Identification and classification, Polymerase chain reaction

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Clobetasol dipropionate 0.05% versus testosterone propionate 2% topical application for severe vulvar lichen sclerosus

Article Abstract:

The corticosteroid clobetasol dipropionate is more effective than testosterone propionate in treating severe vulvar lichen sclerosus. This skin disease on the vulva can cause itching, pain and permanent scarring if left untreated. Researchers compared topical applications of clobetasol dipropionate or testosterone propionate in 20 women with vulvar lichen sclerosus. Although both drugs were effective at three months, by one year more women using clobetasol dipropionate experienced significant improvement compared to those using testosterone propionate.

Health aspects, Evaluation, Drug therapy, Testosterone, Clobetasol

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"Primary" versus "secondary" vulvar vestibulitis: one disease, two variants

Article Abstract:

Primary and secondary vulvar vestibulitis appear to be variations of the same disease. Vulvar vestibulitis is an inflammation of the vagina that makes sexual intercourse painful. If it occurred during the first episode of sexual intercourse it is called primary and if it occurs after many years of pain-free sex, it is called secondary.

Research, Dyspareunia

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