Predicting obesity in young adulthood from childhood and parental obesity

Article Abstract:

Obese children who are still obese as teenagers are likely to be obese adults, especially if one of their parents is also obese. In a study of 135 young adults who were obese, researchers found that those who were obese as young teenagers had a 79% chance of being obese adults if one of their parents was also obese. Those who were obese as young children and had no obese parent only had an 8% chance of being obese as an adult. Those who were obese as teenagers still had a high risk of being obese as adults even if they had no obese parent.

Obesity in children, Childhood obesity

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Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects

Article Abstract:

A study was conducted to determine the serum levels of retinol-binding protein 4, a molecule secreted by adipocytes, correlated with the magnitude of insulin resistance in subjects with obesity, impaired glucose tolerance, or type 2 diabetes and in nonobese, nondiabetic subjects with a strong family history of type 2 diabetes. Levels of adipocytes secreted molecule appear to be elevated in serum before the development of frank diabetes and might be used to identify insulin resistance and associated cardiovascular risk factors.

Protein binding, Insulin resistance

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Interpreting incomplete data in studies of diet and weight loss

Article Abstract:

Several techniques can be used to analyze data in clinical trials of obesity treatments when many of the patients drop out of the study. These techniques include intention-to-treat analysis, completers analysis, last-observation-carried-forward analysis, baseline-carried-forward analysis, and model-based methods. Two studies published in 2003 showed that the Atkins diet was probably not effective over long periods of time, but only 60% of the participants completed each study.

Editorial, Evaluation, Low-carbohydrate diet, Low carbohydrate diet, Atkins diet

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