Preeclampsia is associated with reduced serum levels of placenta growth factor
Article Abstract:
Preeclampsia may be partly caused by low levels of placenta growth factor. Placenta growth factor is a protein in the placenta that causes blood vessels to form. Researchers measured placenta growth factor in blood samples from healthy pregnant women and pregnant women with preeclampsia. Blood levels of placental growth factor increased from the beginning of pregnancy until week 30, when they began to decrease. Women with preeclampsia had lower levels of placental growth factor compared to healthy pregnant women.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1998
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Correlations of placental perfusion and PIGF protein expression in early human pregnancy
Article Abstract:
A study to investigate temporal correlations between maternal serum placenta growth factor levels and placental perfusion in early human pregnancies is illustrated. The significant increase in serum placenta growth factor coincides with the increased perfusion of the maternal/fetal interface at approximately 12 to 14 weeks of gestation suggesting that the placenta growth factor might contribute to assuring adequate vascular development/function of the placenta early in gestation.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
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Low maternal serum levels of placenta growth factor as an antecedent of clinical preeclampsia
Article Abstract:
Low blood levels of a substance called placenta growth factor could identify pregnant women who are at risk of developing a serious complication of pregnancy called preeclampsia. Placenta growth factor is a protein in the placenta that activates blood vessel cells.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2001
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