Prenatal gangrene in association with twin-twin transfusion syndrome

Article Abstract:

Repeated amniocentesis to withdraw fluid allowed both twins to survive twin-twin transfusion syndrome. In twin-twin transfusion syndrome, identical twins share a placenta and abnormal blood vessel connections within it lead to too much amniotic fluid and congestive heart failure in one twin and too little amniotic fluid and growth retardation in the other twin. A woman was diagnosed with this syndrome at 23 weeks gestation. Six amniocenteses were performed over the next nine weeks to remove 1000 to 2000 ml of excess fluid from one twin's amniotic sac. At 32 weeks spontaneous labor began, and a cesarean section was performed. The twin with too little fluid weighed 1100 g. He was anatomically normal. He had a hernia and necrotizing enterocolitis during the postpartum period. The twin with too much fluid weighed 1650 g. His lower left leg was gangrenous and was surgically removed, but otherwise he had only minor complications postnatally.

Case studies, Complications and side effects, Hydramnios, Gangrene

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Twin-to-twin transfusion syndrome: aggressive therapeutic amniocentesis

Article Abstract:

Twin fetuses with twin-to-twin transfusion syndrome may benefit from therapy involving removal of amniotic fluid. Eleven sets of twins with twin-to-twin transfusion syndrome had this therapy while six did not. More treated twins lived than un-treated twins. The smaller of the two twins typically lived longer than the larger twin with the larger twin averaging 36 days and the smaller twin averaging 47 days. An average of 8.0 total liters of amniotic fluid was removed during the treated pregnancies.

Twins

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Changing trends in patient decisions concerning genetic amniocentesis

Article Abstract:

Fewer pregnant women are choosing to have amniocentesis when they are told they may be carrying a child with Down syndrome. This was the conclusion of researchers who studied 53 such women in 1995 and 59 in 1998.

Statistical Data Included, Research, Statistics, Genetic screening, Genetic testing

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