Primary venous thromboembolism and cancer screening
Article Abstract:
Researchers have suggested that the formation of blood clots in the legs and lungs, without a specific risk factor, may be evidence of a hidden cancer. In studies of cancer rates in patients after treatment for primary deep vein thrombosis or pulmonary embolism, such patients appear to have a threefold higher cancer rate in the first six months after the clotting event. Cancer may induce excessive clotting before other symptoms develop. Noninvasive screening, such as mammography, pelvic ultrasound, and prostate cancer tests, may be indicated in patients with such clotting conditions.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
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Venous thromboembolism during pregnancy
Article Abstract:
Excessive blood clotting during pregnancy only occurs in 1 in 1,000 to 1 in 2,000 pregnancies but it can cause serious illness and death. It occurs because of physiological changes in blood vessels during pregnancy and because pregnancy changes blood levels of coagulation factors. Impedance plethysmography and ultrasound can detect blood clotting in the legs and a ventilation-perfusion scan can detect it in the lungs. Women with a history of blood clotting during pregnancy should be treated with subcutaneous heparin. Warfarin can be used after delivery.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
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