Prospective evidence of a circadian rhythm for out-of-hospital cardiac arrests
Article Abstract:
A study of 1,019 patients who were brought to a hospital in cardiac arrest in one year found that when the number of arrests was plotted against the hour of the day, the number of arrests increased steadily from 6 a.m. until it peaked at noon. Circadian rhythms, which are biological rhythms that fluctuate around a 24-hour period, have been found to influence heart attacks, angina, blood pressure and strokes. Furthermore, heart rate, the aggregation of platelets, and blood levels of hormones that regulate the heart and blood vessels all peak in the early morning hours. Treatments for heart disease may be more effective if they are given at specific times of the day.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1992
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Outbreaks of gram-negative bacterial bloodstream infections traced to probably contamination of hemodialysis machines - Canada, 1995; United States, 1997; and Israel, 1997
Article Abstract:
Improper maintenance of a hemodialysis machine resulted in bacterial bloodstream infections (BSIs) in several countries. In 1995, nine Canadian patients on dialysis developed BSIs, as did 10 US and eight Israeli dialysis patients in 1997. All three hemodialysis centers used the Centrysystem 3 hemodialysis machines manufactured by GAMBRO Healthcare. However, personnel at the centers were not aware that the machine had two valves that needed to be disinfected and eventually replaced. A subsequent investigation revealed that the valves had become contaminated and probably caused the outbreaks.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Survival by Time of Day of Hemodialysis in an Elderly Cohort. (Original Contribution)
Article Abstract:
Patients with kidney failure who receive dialysis in the morning may live longer than those who receive it in the afternoon, according to a study of 242 patients with end-stage kidney failure. More research is needed to confirm this conclusion and to determine how morning dialysis differs from afternoon dialysis.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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- Abstracts: Current treatment of patients surviving out-of-hospital cardiac arrest. Improving Survival From Sudden Cardiac Arrest: The Role of the Automated External Defibrillator
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